{"id":98,"date":"2013-07-19T08:28:46","date_gmt":"2013-07-19T13:28:46","guid":{"rendered":"https:\/\/wp.stolaf.edu\/chemistry\/?page_id=98"},"modified":"2013-07-19T08:28:46","modified_gmt":"2013-07-19T13:28:46","slug":"characterization-of-bacterial-small-rnas","status":"publish","type":"page","link":"https:\/\/wp.stolaf.edu\/chemistry\/characterization-of-bacterial-small-rnas\/","title":{"rendered":"Characterization of Bacterial Small RNAs"},"content":{"rendered":"<div data-modular-content-collection><p><strong><a href=\"mailto:pellino@stolaf.edu\">Janice Pellino<\/a>\u00a0\u2013\u00a0<\/strong>Assistant Professor<\/p>\n<p>Research Students<br \/>\nKaren Bieraugel<br \/>\nSeth Huiras<\/p>\n<p>Also pictured is Christopher Roberts<\/p>\n<table style=\"width: 410px\" border=\"0\">\n<tbody>\n<tr>\n<td width=\"392\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" src=\"https:\/\/wp.stolaf.edu\/chemistry\/files\/2013\/07\/hurisrobertskaren-pellinoresearch09.jpg\" width=\"392\" height=\"294\" align=\"left\" \/><\/td>\n<td width=\"196\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>RNAs are key molecules in many cellular processes, acting as information carriers, structural scaffolds, and even catalysts. The recent discovery of a set of gene control pathways that respond to non-coding RNA has revolutionized the way many of us do and think about science. However, many questions remain regarding these small non-coding RNAs, particularly in bacteria. Recent computational studies have identified hundreds of small non-coding RNAs (sRNAs) in bacterial genomes. In the bacterium\u00a0<em>Escherichia<\/em>\u00a0<em>coli\u00a0<\/em>(<em>E. coli<\/em>) alone, close to 100 small RNAs have been identified, however, the function of the majority of these sRNAs remains unknown. A greater understanding of how these sRNAs regulate gene expression in\u00a0<em>E. coli<\/em>, and by extension the closely related bacterium\u00a0<em>Salmonella typhimurium<\/em>, could provide insight into these bacteria\u2019s mechanisms of survival and infectivity. I am studying several bacterial small RNAs to characterize their structures, how they interact with their targets, and their cellular roles. This project combines techniques in biochemistry, molecular biology, biophysics, and genetics.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Janice Pellino\u00a0\u2013\u00a0Assistant Professor Research Students Karen Bieraugel Seth Huiras Also pictured is Christopher Roberts RNAs are key molecules in many cellular processes, acting as information carriers, structural scaffolds, and even [&hellip;]<\/p>\n","protected":false},"author":209,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-98","page","type-page","status-publish","hentry"],"acf":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/pages\/98","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/users\/209"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=98"}],"version-history":[{"count":0,"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/pages\/98\/revisions"}],"wp:attachment":[{"href":"https:\/\/wp.stolaf.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=98"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}